Analytical Biotechnology Laboratory has started from April 2018 to elucidate the principle of biological system which consists of complex interactive network of biological molecules (gene, protein, metabolites, and cell etc). Understanding the mechanism of adaptation, robustness, and evolution by information technologies is beneficial for multiple fields including information, engineering, agricultural and medical sciences. We are trying to achieve the quantitative elucidation of the property of biological system by analyzing various kinds of molecules using advanced analytical technologies. The extracted characteristics of the system by reconstructing the operation principle in sillico and in vitro will contribute to the efficient and novel bioproduction and drug discoveries.